Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
---|---|---|---|---|---|---|---|---|---|
CRC | rs75541583 | chr1:26694059 | G/C | 6.1E-5 | 360 | 22.37 | 24.5 | 17.15 | KM Plot |
CRC | rs7555966 | chr1:11664772 | G/A | 3.3E-6 | 367 | 9.37 | 18.82 | 24.5 | KM Plot |
CRC | rs75728990 | chr6:53528375 | C/T | 2.75E-5 | 372 | 22.3 | 24.77 | 7.13 | KM Plot |
CRC | rs761081 | chr1:11664197 | T/C | 3.35E-6 | 364 | 9.37 | 19.1 | 24.5 | KM Plot |
CRC | rs761082 | chr1:11664013 | C/A | 2.52E-5 | 361 | 10.07 | 20.4 | 24.7 | KM Plot |
CRC | rs76135039 | chr6:53529138 | C/T | 2.75E-5 | 372 | 22.3 | 24.77 | 7.13 | KM Plot |
CRC | rs76354454 | chr22:50206573 | G/A | 1.53E-8 | 372 | 22.25 | 25.28 | 7.9 | KM Plot |
CRC | rs76518692 | chr7:62059897 | C/G | 5.76E-7 | 365 | 23.83 | 20.3 | 11.27 | KM Plot |
CRC | rs76994901 | chr6:53528523 | T/C | 2.75E-5 | 372 | 22.3 | 24.77 | 7.13 | KM Plot |
CRC | rs7700955 | chr5:54668531 | T/C | 6.03E-5 | 373 | 22.32 | 23.43 | 9.67 | KM Plot |
CRC | rs7705875 | chr5:54596391 | C/T | 5.47E-5 | 372 | 22.3 | 24.35 | 9.67 | KM Plot |
CRC | rs7715368 | chr5:54653708 | T/C | 6.03E-5 | 373 | 22.32 | 23.43 | 9.67 | KM Plot |
CRC | rs77164467 | chr6:53529687 | G/C | 2.75E-5 | 372 | 22.3 | 24.77 | 7.13 | KM Plot |
CRC | rs7721304 | chr5:54590269 | A/G | 4.95E-5 | 371 | 22.32 | 23.43 | 9.67 | KM Plot |
CRC | rs77261700 | chr15:76785649 | T/A | 1.55E-6 | 371 | 22.53 | 22.32 | 7.6 | KM Plot |